Anti‐epilepsy drug therapy in a dox‐regulatable TDP‐43 mouse model of ALS‐FTD with seizures

Alzheimers Dement · 2024 · PMC11713330

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showed a trendp = 0.12not close (p > 0.1)

Mean hippocampus mass at 6 weeks off‐DOX was similar for both groups (21.7mg LEV, 22.mg VEH; Student’s t‐test, p = 0.84) but the LEV treated group showed a trend towards reduced cortical atrophy (mean motor cortex thickness on H&E stained sections: 943μm LEV, 870μm VEH; Student’s t‐test, p = 0.12).

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