White Matter Changes in Alzheimer’s and Treated Huntington’s Disease Mouse Models Detected by Diffusion MRI

Alzheimers Dement · 2024 · PMC11715851

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an increasing trendno p-value reported

HD mice showed an increasing trend in AWF and RK and decreases in RD in both ROIs vs WT, suggesting increased myelination.

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showed a trendno p-value reported

In HD mice, both diffusion MRI and histology showed a trend towards increased myelin, which was reversed by LM11A‐31 treatment. pmc-status-qastatus 0 pmc-status-live yes pmc-status-embargo no pmc-status-released yes pmc-prop-open-access yes pmc-prop-olf no pmc-prop-manuscript no pmc-prop-legally-suppressed no pmc-prop-has-pdf yes pmc-prop-has-supplement no

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.