Efficacy, safety and treatment satisfaction of transition to a regimen of insulin degludec/aspart: A pilot study.

A meta-analysis encompassing eight studies comparing twice-daily IDegAsp to twice-daily traditional pre-mixed insulin[ 10 , 14 , 21 - 26 ] showed a significant reduction in HbA1c levels for both regimens, yet the difference between the groups did not reach statistical significance.

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There appeared to be a decreasing trend in the frequency of hypoglycemic events; however, this was not statistically significant ( P = 0.07) (Table 2 ).

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