<i>Salvia miltiorrhiza</i> Root Extract for Men with Lower Urinary Tract Symptoms: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial.

At the end of the study period, the change in DHT levels did not reach statistical significance, with the S-400 group experiencing an increase of 25.95 ± 91.78 ng/mL and the S-800 group an increase of 9.57 ± 102.68 ng/mL, while the placebo group showed a slight decrease (−1.10 ± 64.27 ng/mL) ( p = 0.4178).

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The S-800 group also had an increase in overall satisfaction (Δ12wk: +0.85 ± 1.27, p = 0.0012), indicating a positive trend toward treatment efficacy.

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