A meta-analysis on 11 randomized controlled trials showed a trend to decrease cardiac volume indices and improve of functional parameters in patients using SGLT2i, which were not statistically significant [ 19 ].
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Is early use of sodium-glucose cotransporter type 2 inhibitor (SGLT2i) necessary even in diabetic patients without cardiovascular disease: a prospective study regarding the effect of SGLT2i on left ventricular diastolic function.
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