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Mural Cells Initiate Endothelial-to-Mesenchymal Transition in Adjacent Endothelial Cells in Extracranial AVMs.

Cells · 2024 · PMC11727354 · PMID 39768212

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In addition, the mesenchymal genes smooth muscle alpha-2 actin ( ACTA2/α-SMA ) [ 51 ], vimentin ( VIM ) [ 53 ], and N-cadherin ( CDH2 ) [ 54 , 55 ] were all upregulated in eAVM tissues compared to adjacent tissue controls, although ACTA2 did not reach statistical significance.

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