Barely Significant
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Biochemical liver damage during gender affirming therapy in trans adults assigned female at birth: a meta-analysis.

J Endocrinol Invest · 2025 · PMC11729134 · PMID 38909133

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showed a trendno p-value reported
The figure for ALT, the most specific marker of liver damage, showed a trend towards stabilization at 24 months, supporting the idea that these changes were clinically not significant and transient in most cases.

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