Furthermore, CD8 + , CD4 + , and CD163 + cell densities showed a trend of higher levels during T-DXd treatment ( Fig. 4A ; Supplementary Fig.
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The Tumor Immune Microenvironment and Therapeutic Efficacy of Trastuzumab Deruxtecan in Gastric Cancer.
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In this study, we found a nonsignificant trend between various baseline immune cell densities and T-DXd efficacy and detected a significant difference between baseline CD20 + cell densities in responders and nonresponders.