Although younger age ( p = 0.171), MGMT promoter methylation ( p = 0.145), absence of TERT promoter mutation ( p = 0.290) indicated a tendency towards a favorable prognosis, these factors did not reach statistical significance (Supplemental Fig.
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High p16<sup>INK4A</sup> expression in glioblastoma is associated with senescence phenotype and better prognosis.
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