Reconstructed Epidermis Produced with Atopic Dog Keratinocytes Only Exhibit Skin Barrier Defects after the Addition of Proinflammatory and Allergic Cytokines.

JID Innov · 2025 · PMC11730559 · PMID 39811760

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a decreasing trendno p-value reported

A decreasing trend in the TEER values was observed, with 10,700 (range = 5000–13,600) Ω × cm 2 in the control group; 9433 (4800–11,800) Ω × cm 2 for the group treated with the medium concentration of cytokines; and 6900 (4200–11,700) Ω × cm 2 for the group treated with the highest concentration, but the differences were not statistically significant ( P = .2), possibly because of high interindividual variations.

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did not reach statistical significanceno p-value reported

Cdsn expression was also reduced with the individual cytokines, but the difference did not reach statistical significance.

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