Therapeutic potential of brentuximab vedotin in breast cancer and lymphoma via targeted apoptosis and gene regulation.

Sci Rep · 2025 · PMC11730651 · PMID 39805861

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0010

boldest claim

The sentences

highly significantp < 0.001actually significant

CDH1 showed a highly significant upregulation ( p < 0.001*), which was more pronounced than initially characterized.

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a clear trendno p-value reported

For the cancer cell lines (MCF-7, MDA-MB-231, T47D, and U937), there is a clear trend of increasing apoptosis over time, with late apoptosis becoming predominant by T3.

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