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Comparative efficacy and safety of sitagliptin or gliclazide combined with metformin in treatment-naive patients with type 2 diabetes: A single-center, prospective, randomized, controlled, noninferiority study with genetic polymorphism analysis.

Medicine (Baltimore) · 2025 · PMC11730665 · PMID 39792745

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showed a trendno p-value reported
The sitagliptin group achieved more rapid reductions in blood glucose levels and higher FPG compliance rates and showed a trend towards reductions in body weight and BMI, with a similar risk of hypoglycemia.

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