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Creatinine production rate is an integrative indicator to monitor muscle status in critically ill patients.

Crit Care · 2025 · PMC11731194 · PMID 39810218

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Furthermore, a greater decrease in CPR from day 1 to days 2, 3, or 5 was associated with worse survival, although the decreases on days 2 and 3 did not reach statistical significance (Supplemental Tables 10 – 12 ).

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