Exploring the Relationship Between Humoral and Cellular T Cell Responses Against SARS-CoV-2 in Exposed Individuals From Emilia Romagna Region and COVID-19 Severity.

HLA · 2025 · PMC11731316 · PMID 39807702

Europe PMC DOI

hedged sentences

0.0530

closest p · 1.1× alpha

0.0590

boldest claim

The sentences

borderline significancep = 0.053so close (0.05 < p ≤ 0.1)

Regarding CD, HLA‐A*03:01 and A*24:02 reached a borderline significance in negatively affecting the CD of individuals with acute COVID‐19 infection compared to those with sp status ( p = 0.053 and p = 0.06, respectively), while carriers of A*11:01 had significantly decreased CD compared to sp individuals.

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reached borderline significancep = 0.059so close (0.05 < p ≤ 0.1)

HLA‐A*02:01 is a common allele that, in our study, was associated with increased CB ( p = 0.008) and reached borderline significance with increased median CD ( p = 0.059).

also in 93 other papers

borderline significantno p-value reported

Individuals carrying HLA‐A*02:01 ( p = 0.059) or HLA‐A*02:05 ( p = 0.055) in the sp group also demonstrated borderline significant increases and decreases in CD median compared to the group median, respectively (Figure 5B ).

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