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Chronic small intestinal helminth infection perturbs bile acid homeostasis and disrupts bile acid signaling in the murine small intestine.

Front Parasitol · 2023 · PMC11731828 · PMID 39816838

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While downregulation of Slc51a (encodes OSTα) during helminth infection did not reach statistical significance in the proximal small intestine, Slc51a was modestly but significantly downregulated during helminth infection in the ileum of female mice only ( Figures 2C, D ).

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