After adjustment, SGLT2i was found to be the only class of anti-diabetes drug with an independently positive impact on renin level with a B value of 30.186 and a 95% confidence interval of 1.71 to 58.662 ( P =0.038), while no other anti-diabetes drug had a significant impact and sulfonylurea was only borderline associated with renin level but did not reach statistical significance (B value: 21.143, 95% CI: −2.729─45.014, P =0.082).
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Analysis of the Endocrine Responses to Anti-Diabetes Drugs: An Issue of Elevated Plasma Renin Concentration in Sodium-Glucose Co-Transporter 2 Inhibitor.
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0.0820