Single-cell analysis identifies the CNP/GC-B/cGMP axis as marker and regulator of modulated VSMCs in atherosclerosis.

Nat Commun · 2025 · PMC11735800 · PMID 39814746

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a strong trendno p-value reported

Interestingly, plaques of GC‐B smko mice showed a strong trend toward more X‐gal + cells compared with plaques of control mice (GC-B smko : 5 ± 2 vs. control: 2 ± 0.4 X‐gal + cells per positive section, n.s.) and they contained significantly more X‐gal + cells than the media (Fig. 6h ).

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