Disease characteristics and outcomes of acute myeloid leukemia in germline <i>RUNX1</i> deficiency (Familial Platelet Disorder with associated Myeloid Malignancy).

Hemasphere · 2025 · PMC11735945 · PMID 39822584

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

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boldest claim

The sentences

showed a trendp = 0.06so close (0.05 < p ≤ 0.1)

After matching, FPDMM‐AML patients again showed a trend toward a favorable outcome, albeit without statistical significance ( p = 0.06) (Figure 5F ).

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an overall trendno p-value reported

FPDMM‐AML showed an overall trend toward lower frequencies of cytogenetic aberrations in comparison to HOVON RUNX1 ‐mutated AML (Figure 4C ), including monosomal karyotype (0/35, 0% vs. 12/206, 5.8%) and monosomy 5 or 5q deletions (0/35, 0% vs. 12/206, 5.8%).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.