Interestingly, there was a trend towards a positive correlation between USP35 and BRD4 protein level in the CPTAC database, although it did not reach statistical significance (Supplementary Fig. 7A ), considering that samples in the CPTAC database consist of different subtypes of breast cancer.
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USP35 promotes the growth of ER positive breast cancer by inhibiting ferroptosis via BRD4-SLC7A11 axis.
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