Overall, cases classified as AD by the CSF biomarker profile, had significantly higher levels of AT8-positive tau aggregates and a strong trend for higher total tau (CI 95 = −2.62, 54.65) and Aβ (CI 95 = −2.83, 71.54) aggregate levels.
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Ultrasensitive Protein Aggregate Quantification Assays for Neurodegenerative Diseases on the Simoa Platform.
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