Impaired Presynaptic Function Contributes Significantly to the Pathology of Glycine Receptor Autoantibodies.

Although expression of GlyR subunits (labelled by mab4a), VGAT, gephyrin, syndapin I, and GABA A R did not show significant changes between groups ( Figure 1 , D , F , G , H , I ), expression of GlyT2 was significantly increased in the presence of Pat23 serum after 4 days incubation ( p = 0.0018; Figure 1E ) and still showed a trend toward higher GlyT2 expression after 2 days of recovery.

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