Targeting unique ligand binding domain structural features downregulates DKK1 in Y537S ESR1 mutant breast cancer cells.

Breast Cancer Res · 2025 · PMC11742495 · PMID 39825366

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showed a trendno p-value reported

Ex vivo analysis of common sites of breast cancer metastasis (liver, brain, femurs, uterus) showed a trend toward significant decrease with increasing dose of T6I-29–1 A (Fig. 5 G).

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