CRAT downregulation promotes ovarian cancer progression by facilitating mitochondrial metabolism through decreasing the acetylation of PGC-1α.

Cell Death Discov · 2025 · PMC11743791 · PMID 39828731

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failed to reach statistical significanceno p-value reported

In agreement with this, prognostic analysis using the online Kaplan-Meier plotter database also indicated that OC patients with low CRAT expression had poorer overall survival (OS), although failed to reach statistical significance, and progression-free survival (PFS) than those with high CRAT expression (Fig. 1 G and H).

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