Dysregulation of the Kynurenine Pathway in Relapsing Remitting Multiple Sclerosis and Its Correlations With Progressive Neurodegeneration.

Neurol Neuroimmunol Neuroinflamm · 2025 · PMC11744609 · PMID 39823555

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did not reach statistical significanceno p-value reported

In addition, while the correlation observed did not reach statistical significance, the data suggest a potential relationship between retinal ganglion cell and axonal loss—considered indicative of general neurodegeneration in the disease—and various components of the KP pathway (eTable 5).

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