Anticoagulation Status and Outcome in Cerebral Venous Thrombosis: A Single-Center Retrospective Study from South India.

In the acute phase, low-molecular weight or unfractionated heparin is initiated followed by maintenance anticoagulation with vitamin K antagonist for a variable period depending on the etiology of CVT.[ 5 , 6 ] While this approach is recommended by most guidelines and is standard clinical practice, there is surprisingly limited evidence supporting its benefits, both in the acute and long term.[ 7 , 8 ] A Cochrane review investigating the effectiveness and safety of anticoagulant therapy in cerebral venous sinus thrombosis found a 13% reduction in death or dependency, which did not reach statistical significance.[ 9 ] The recommendations are guided by consensus and expert opinions, with the quality of evidence ranging from low to very low and strength of recommendations remaining weak.[ 10 , 11 , 12 ] Moreover, the recommended target international normalized ratio (INR) of between 2 and 3 is mostly extrapo

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