APOBEC3A deaminates CTG hairpin loops to promote fragility and instability of expanded CAG/CTG repeats.

Proc Natl Acad Sci U S A · 2025 · PMC11745325 · PMID 39772743

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hedged sentence

0.0540

closest p · 1.1× alpha

0.0540

boldest claim

The sentences

nearly significantP = 0.054so close (0.05 < p ≤ 0.1)

STAT1, STAT2, and CD16 were not significantly elevated in HD brains compared to normal controls (CD16 was nearly significant, P = 0.054) and only STAT2 is significantly correlated with A3A expression in HD brains (STAT2, P = 0.012) ( SI Appendix , Fig.

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