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Multiplex immunohistochemistry to explore the tumor immune microenvironment in HCC patients with different GPC3 expression.

J Transl Med · 2025 · PMC11748271 · PMID 39838375

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In addition, we also analyzed the spatial analysis of CD8 + PD-L1 + cells within these 3 radii, and the CD8 + PD-L1 + cells were all higher in the high GPC expression group than in the low GPC3 expression group, but did not reach statistical significance (Fig S2).

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