Barely Significant
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KEAP1 mutations as key crucial prognostic biomarkers for resistance to KRAS-G12C inhibitors.

J Transl Med · 2025 · PMC11748609 · PMID 39825361

1
hedged sentence
0.0700
closest p · 1.4× alpha
0.0700
boldest claim

The sentences

did not reach statistical significanceP = 0.07so close (0.05 < p ≤ 0.1)
PD-L1 expression levels: a gentle nudge in prognostic forecasting In the subgroup analysis of PD-L1 expression levels, patients with PD-L1-negative status showed a higher ORR compared to PD-L1-positive patients, although this difference did not reach statistical significance (P = 0.07) (Fig. 8 A).

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