Follicular fluid-derived exosomes rejuvenate ovarian aging through miR-320a-3p-mediated FOXQ1 inhibition.

There were no difference in the number of female ( P > 0.05, Fig.S3K ) in the Y-exos group, however, the pups per female have an increasing trend ( P > 0.05, Fig.

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According to a new report in Lancet , it is estimated that by 2050, 151 countries, including China, will have an extremely declining fertility rate and a clear trend of advanced reproductive age due to improvements in women’s education levels, increased employment pressure, and easier access to contraception [ 3 ].

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