Effect of radiotherapy exposure on fruquintinib plus sintilimab treatment in refractory microsatellite stable metastatic colorectal cancer: a prospective observation study.

J Immunother Cancer · 2025 · PMC11749590 · PMID 39755582

Europe PMC DOI

hedged sentence

0.1600

closest p · 3.2× alpha

0.1600

boldest claim

The sentences

did not reach statistical significancep=0.16not close (p > 0.1)

In addition, the abundance of Bifidobacterium did not have a significant impact on PFS or OS (p > 0.05; Online supplemental figure S1D, E ); the higher abundance of Lactobacillus and Bifidobacterium significantly improved PFS (p = 0.02), but did not reach statistical significance for OS (p=0.16; Online supplemental figure S1F, G ).

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