Early treatment discontinuation in patients with deficient mismatch repair or microsatellite instability high metastatic colorectal cancer receiving immune checkpoint inhibitors.

A trend towards a higher number of patients more than 70 years old (37% vs 29%), BRAF V600E mutation (39% vs 31%), non-mucinous histology (75% vs 68%), absence of lung metastases (91% vs 85%) and ICIs received in an earlier line (49% vs 42% for first and 36% vs 33% for second line) was observed for ETD as compared with LTD, respectively, but did not reach statistical significance.

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