Future Directions in the Management of Classic Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency.

In the randomized double-blind placebo-controlled trial for the poor control group, the placebo-adjusted reduction from baseline in A4 did not reach statistical significance after 12 weeks of treatment with tildacerfont 200 mg once daily ( 41 ), and the trial was terminated.

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