Notably, PD1+ Tregs significantly declined over time when considered as percentages over total CD4 T cells (MR= 0.956, 95%CI 0.921;0.993, p=0.019), while when measured as percentages over Tregs and as concentrations this trend did not reach statistical significance ( Supplementary Table 2 ).
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Tregs levels and phenotype modifications during Amyotrophic Lateral Sclerosis course.
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