We also observed a strong trend toward increased waking gamma power in Fmr1 KO mice ( Figure S3 F), consistent with previous reports. 31 , 32 , 33 , 34 Both excitation and inhibition are dysregulated in two mouse models of ASD Our findings indicate that the E/I ratio is dysregulated across the day in two ASD-related mouse lines.
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Daily oscillation of the excitation/inhibition ratio is disrupted in two mouse models of autism.
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