Combining SKY92 gene expression profiling and FISH (according to R2-ISS) defines ultra-high-risk Multiple Myeloma.

Hemasphere · 2025 · PMC11754766 · PMID 39850647

Europe PMC DOI

hedged sentence

0.0450

closest p · 0.9× alpha

0.0450

boldest claim

The sentences

showed a trendp = 0.045actually significant

However, we did not observe a significant prognostic impact of HR FISH as defined by the R2‐ISS classification in NDMM patients, and in RRMM, HR FISH showed a trend toward shorter PFS (median: 6.5 vs. 11.6 months, p = 0.045) and OS (median: 19.7 months vs. not reached, p = 0.11) (Supporting Information S1: Figure S2 ).

also in 26,766 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.