Efficacy of cartilage-targeted IGF-1 in a mouse model of growth hormone insensitivity.

Front Endocrinol (Lausanne) · 2024 · PMC11756323 · PMID 39850478

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did not reach statistical significanceno p-value reported

Interestingly, the once-daily injection of CV1574-1 significantly increased the overall growth plate height compared to saline ( Figure 2D ), while the IGF-1 twice-daily injection showed a tendency towards increased growth plate height compared to saline but did not reach statistical significance.

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