Nationwide multi-centric prospective study for the identification of biomarkers to predict the treatment responses of nivolumab through comprehensive analyses of pretreatment plasma exosome mRNAs from head and neck cancer patients (BIONEXT study).

Front Immunol · 2024 · PMC11758179 · PMID 39867897

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hedged sentence

0.0520

closest p · 1.0× alpha

0.0520

boldest claim

The sentences

near-significantP = 0.052so close (0.05 < p ≤ 0.1)

Consistent with the previous finding that only specific genes demonstrated significant correlations ( 25 ), PEX HLA-E mRNA showed a near-significant ( P = 0.052) correlation with tumor HLA-E mRNA among the 6 genes ( Figure 5A ).

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