Irisin and Metastatic Melanoma: Selective Anti-Invasiveness Activity in BRAF Wild-Type Cells.

Int J Mol Sci · 2025 · PMC11765811 · PMID 39859367

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showed a trendno p-value reported

As shown in Figure 4 , HBL showed a trend of downregulation of uPA and uPAR , while LND1 showed a significant reduction in uPA and PAI-1 ( p < 0.05) upon irisin treatment compared to untreated cells, respectively.

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