Barely Significant
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A Haplotype GWAS in Syndromic Familial Colorectal Cancer.

Int J Mol Sci · 2025 · PMC11765965 · PMID 39859530

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borderline significantno p-value reported
A first comparison of the 10 loci identified in the previous study, with findings in this study, noted that all 10 were confirmed with statistically significant positive ORs and statistically significant results, except the locus on chromosome 16q23.3 and the gene CDH13 , which was only borderline significant at the exact positions ( Table 1 ).

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The current study suggested that geographically better-matched controls resulted in better risk stratification as the odds ratio for the respective loci was higher, even though the cohort was smaller, and the results did not reach statistical significance.

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