MYC Overexpression Enhances Sensitivity to MEK Inhibition in Head and Neck Squamous Cell Carcinoma.

In Western blotting analysis, MYC overexpression showed a trend toward decreased abundance of p27 ( Figure 4 (Cb), bands 5 and 6 vs. bands 1 and 2; Figure 4 (Db)) but had no significant effect on p21 levels ( Figure 4 (Ca), bands 5 and 6 vs. bands 1 and 2; Figure 4 (Da)).

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