Decreased voluntary alcohol intake and ventral striatal epigenetic and transcriptional remodeling in male Acss2 KO mice.

Neuropharmacology · 2025 · PMC11771284 · PMID 39653249

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hedged sentences

0.0537

closest p · 1.1× alpha

0.0537

boldest claim

The sentences

did not reach statistical significancep = 0.0537so close (0.05 < p ≤ 0.1)

1D ), this effect did not reach statistical significance (two-way ANOVA genotype effect F 1,34 = 3.995, p = 0.0537).

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a decreasing trendno p-value reported

This possibility is further supported by our analysis of cumulative ethanol intake, which revealed a decreasing trend in Acss2 KO mice during the first (2BC) week of our DID paradigm ( Fig. 1C ), and reached statistical significance during the second (1B) week ( Fig. 1F ).

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