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Cause-Specific Mortality and Prognostic Impact of Comorbidity in Japanese Patients With Chronic Lymphocytic Leukemia.

Cancer Med · 2025 · PMC11773378 · PMID 39873172

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In the frontline setting, the use of BTKi did not reach statistical significance in treatment durability (Figure S4B ); however, the observed two cases of early treatment change within 2 years were both in‐class switching (i.e., ibrutinib to acalabrutinib): one due to an ibrutinib‐induced rash and the other due to physician's preference.

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