Spinocerebellar ataxia type 17: report of a family with reduced penetrance of an unstable Gln49 TBP allele, haplotype analysis supporting a founder effect for unstable alleles and comparative analysis of SCA17 genotypes.

BMC Med Genet · 2005 · PMC1177950 · PMID 15989694

Europe PMC DOI

hedged sentences

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closest p · 0.0× alpha

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boldest claim

The sentences

highly significantp < 5 ×10 -6actually significant

The likelihood ratio test suggested a highly significant linkage disequilibrium between D6S446 and D6S1590 (p < 5 ×10 -6 ).

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nominally significantno p-value reported

Although the unstable repetitive sequence is linked with one of the three more commonly prevalent haplotypes, statistics point to a nominally significant likelihood that our observation reflects a founder effect rather than coincidence by chance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.