At the level of the SDI, in 2021, the age-standardized DALYs rate across 204 countries showed a trend of first increasing and then decreasing with rising SDI ( Supplementary Figure 5B ).
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Global, regional, and national trends in colorectal cancer burden from 1990 to 2021 and projections to 2040.
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The global age-standardized DALYs rate was 283.24 per 100,000 population, showing a decreasing trend compared to 1990 (AAPC: -0.73, 95% CI: -0.82 to -0.64) ( Table 3 ).