Hormone replacement therapy, menopausal age and lifestyle variables are associated with better cognitive performance at follow-up but not cognition over time in older-adult women irrespective of APOE4 carrier status and co-morbidities.

Front Dement · 2024 · PMC11782126 · PMID 39897117

Europe PMC DOI

hedged sentences

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

approached significancep = 0.08so close (0.05 < p ≤ 0.1)

A diagnosis of diabetes showed an association that approached significance ( p = 0.08).

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a trend toward significancep = 0.08so close (0.05 < p ≤ 0.1)

Our study did not find any influence of comorbidities, such as cancer, hypertension and diabetes, although the latter did show a trend toward significance ( p = 0.08) in our first model.

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