<i>Fusobacterium nucleatum</i> upregulates the immune inhibitory receptor <i>PD-L1</i> in colorectal cancer cells via the activation of ALPK1.

Gut Microbes · 2025 · PMC11784648 · PMID 39881579

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a clear trendno p-value reported

showed a clear trend toward the induction of CXCL8 release in HT-29 cells ( Figure 1a ).

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&lt;i&gt;Fusobacterium nucleatum&lt;/i&gt; upregulates the immune inhibitory receptor &lt;i&gt;PD-L1&lt;/i&gt; in colorectal cancer cells via the activation of ALPK1.

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<i>Fusobacterium nucleatum</i> upregulates the immune inhibitory receptor <i>PD-L1</i> in colorectal cancer cells via the activation of ALPK1.