Cellular senescence-associated gene IFI16 promotes HMOX1-dependent evasion of ferroptosis and radioresistance in glioblastoma.

Nat Commun · 2025 · PMC11785807 · PMID 39890789

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Recent investigations have highlighted the evolutionary trajectory of gliomas during treatment and showed a trend from nascent to old tumors during therapy 4 , 5 , suggesting potential cellular senescence during GBM treatment.

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