moderately significantp < 0.027
Time trends in biological endpoints at the reference sites No statistically significant time trends were observed in any biological endpoints at the reference sites in either herring gulls or Caspian terns, except for a moderately significant increasing trend (Jonkheere p < 0.027) of low magnitude (increasing <10% over 9 years) in the PHA skin response of herring gulls at the Pipe Island Twins.