An XBB.1.5-based inactivated SARS-CoV-2 vaccine partially protects against XBB.1.5 and JN.1 strains in hamsters.

Vaccinations led to remarkable reductions in virus titers relative to mock-immunization at 4 days post-infection, although the difference in virus titers in the lungs between the control hamsters and the immunized hamsters did not reach statistical significance (Fig. 2D ).

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