Exploration of the mechanism of Lithospermum erythrorhizon oil in treating atopic dermatitis based on network pharmacology and experimental validation of the PI3K-Akt pathway regulation.

Heliyon · 2025 · PMC11791135 · PMID 39906865

Europe PMC DOI

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closest p · 1.0× alpha

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boldest claim

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did not reach statistical significanceP > 0.05actually significant

An in-depth comparison revealed that the Positive Control Group had an even lower IL-4 level than the Treatment Group (P < 0.05), while the difference in IL-13 levels did not reach statistical significance (P > 0.05), suggesting a potentially greater regulatory effect of the treatment on IL-4 within the Positive Control Group.

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